The Children’s Diabetes Centre is now recruiting for a new continuous glucose monitoring study.
Study summary:
This study will investigate how continuous glucose monitoring, using two different Medtronic sensors that are not yet approved for sale in Australia, compare to blood glucose readings and to each other over a ten-day period. One sensor (Harmony 1) requires daily calibrations and is intended to provide sensor glucose readings for ten days. The other (Guardian 3) requires twice daily calibrations and is intended to provide sensor glucose readings for only seven days. For this study, the Guardian 3 readings are blinded – which means you will not be able to see the sensor glucose readings. However, the readings from the Harmony 1 sensor will be displayed in real-time.
Study requirements: For this study you will wear two of each type of sensor (one in each upper arm, and one on each side of your tummy), for ten days. Half the people in the study (Group 1), will have their sensors inserted and their CGM started approximately 12 hours before their first in-clinic visit. The other half (Group 2) will have their sensors inserted and their CGM started on the day of their first in-clinic visit.
For this study, you will need to attend the Research Unit at PMH on 4-5 separate days:
- Visit 1 is for study familiarisation and, if you are age <35 years - an assessment of VO2 peak (measure of fitness)
- Pre-visit 2 is for sensor commencement for Group 1 only. For Group 2, Pre-visit 2 and Visit 2 are on the same day
- Visit 2 is for a 10 - 12 hour in-clinic study, requiring frequent blood sampling through a drip, and includes a hypo and hyper challenge
- Visit 3 is for a 10 - 12 hour in-clinic study, requiring frequent blood sampling through a drip, and includes a hypo and hyper challenge
- Visit 4 is for a 10 - 12 hour in-clinic study, requiring frequent blood sampling through a drip, and includes a hypo and hyper challenge
Principal Investigator: Professor Tim Jones – Head of the Department of Endocrinology and Diabetes at Princess Margaret Hospital (PMH), and Co-Director of the Children’s Diabetes Centre, The Kids Research Institute Australia.
If you have Type 1 Diabetes and are aged 13 to 55 years and think this study interests you, please contact Niru Paramalingam – clinical research coordinator, Diabetes Research Team on niru.paramalingam@health.wa.gov.au or (08) 9340 8671.